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Kinetic and Mechanistic Data for a Human Physiologically Bases Pharmacokinetic (PBPK) Model for Acrylamide

Despite gaps and limitations to the database, model parameters have been estimated to provide a relatively consistent description of the kinetics of acrylamide and glycidamide using a single set of values (with minor adjustments in some cases). This review, published in Advances in Experimental Medicine and Biology (2005;561:117-125), discusses the PBPK model for acrylamide.

Read more about Kinetic and Mechanistic Data for a Human Physiologically Bases Pharmacokinetic (PBPK) Model for Acrylamide

Human Exposure and Internal Dose Assessments of Acrylamide in Food

This review, published in Food and Chemical Toxicology (2005;43:365-410), provides a framework contributing to the risk assessment of acrylamide in food. It is based on the outcome of the ILSI Europe FOSIE process, a risk assessment framework for chemicals in foods and adds to the overall framework by focusing especially on exposure assessment and internal dose assessment of acrylamide in food.

Read more about Human Exposure and Internal Dose Assessments of Acrylamide in Food

Beverage Caffeine Intake in US Consumers and Subpopulations of Interest: Estimates from the Share of Intake Panel Survey

Concerns exist about the potential adverse health effects of high consumption of dietary caffeine, especially in children and pregnant women. This article, published in Food and Chemical Toxicology (2004;42:1923-1930), discusses the Share of Intake Panel survey.

Read more about Beverage Caffeine Intake in US Consumers and Subpopulations of Interest: Estimates from the Share of Intake Panel Survey

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