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ILSI North America is committed to sharing the results of the research we support, regardless of the outcomes. Our publications undergo stringent peer-review by qualified experts prior to publication and include disclosure of all sources of funding.

Establishing What Constitutes a Healthy Human Gut Microbiome: State of the Science, Regulatory Considerations, and Future Directions

ILSI North America previously took on the task of defining a “healthy gut microbiome,” and the outcome of this effort was published by Backhed et al. in 2012. Since that time, the body of work on gut microbiome has grown exponentially. In 2018, >40 invited academic, government, and industry experts gathered to evaluate progress toward this definition and explore the question: Can a Healthy Gut Microbiome be Defined Through Quantifiable Characteristics?

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Role for Diet in Normal Gut Barrier Function: Developing Guidance within the Framework of Food-Labeling Regulations

This perspective article summarizes the present scientific evidence focused on 1) the gut barrier as an important component of normal gastrointestinal structure and function in human health, 2) currently available modalities to describe the intestinal barrier and quantify its function in humans, and 3) providing possible associations between diet and normal gut barrier function among healthy or at-risk people.

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