The Lipids Committee addresses emerging issues and trends associated with dietary fats and oils to inform evidence-based nutrition guidance and to improve human health.
Research Focus Areas
- Address questions related to the role of fat and its dietary sources in popular diets, as well as public health recommended eating patterns.
- Evaluate genotype and/or phenotype data from existing and emerging sources on how individuals respond differently to specific lipids, including on nutrient status and on health outcomes.
- Support evidence-based decision making on changes in the dietary fats and oils applications in the food supply that have perceived or potential health effects.
COMMITTEE MEMBERS
Archer Daniels Midland Company
Cargill, Incorporated
DSM-Firmenich
Mondelēz International
ACADEMIC ADVISOR
Catherine Field, PhD, University of Alberta
GOVERNMENT LIAISON
David Baer, PhD, US Department of Agriculture
Beltsville Human Nutrition Research Center
Recent Work:
Maintaining the Quality of Unsaturated Oils in Food Service Frying Processes
Oxidation of unsaturated oils is an important issue as the food industry adjusts food preparation practices, such as frying, that comply with legislation prohibiting the use of partially hydrogenated oils (PHO). This brief review focuses on frying applications and includes a summary of lipid oxidation’s potential effects on health and flavor, as well as strategies to curb lipid oxidation during frying. An infographic is also provided to increase awareness and support informed decision-making.
Long-chain omega-3’s (DHA & EPA)
- NUTRITION 2023 session on “It’s Time to Quantify Intake Recommendations for Dietary Bioactives” featured three bioactives, including quantifying intakes for long-chain omega-3’s (DHA & EPA) for full-term pregnancy (click here for the session overview). This supports a broader strategy to support science-based health messaging about dietary components that do not currently have established minimum intake recommendations.
Projects Supported by the Committee:
Publications
Dietary Reference Intakes Based on Chronic Disease Endpoints: Outcomes from a Case Study Workshop for Omega 3’s EPA and DHA
Applied Physiology, Nutrition and Metabolism, 2021
Common Genetic Variations Involved in the Inter-Individual Variability of Circulating Cholesterol Concentrations in Response to Diets: A Narrative Review of Recent Evidence
Nutrients, 2021
The number of nutrigenetic studies dedicated to the identification of single nucleotide polymorphisms (SNPs) modulating blood lipid profiles in response to dietary interventions has increased considerably over the last decade. However, the robustness of the evidence-based science supporting the area remains to be evaluated. The objective of this review was to present recent findings concerning the effects of interactions between SNPs in genes involved in cholesterol metabolism and transport, and dietary intakes or interventions on circulating cholesterol concentrations, which are causally involved in cardiovascular diseases and established biomarkers of cardiovascular health.
A Combination of Single Nucleotide Polymorphisms is Associated with the Interindividual Variability in the Blood Lipid Response to Dietary Fatty Acid Consumption in a Randomized Clinical Trial
The American Journal of Clinical Nutrition, 2021
Blood lipid concentrations display high interindividual variability in response to dietary interventions, partly due to genetics. The study reports combinations of single nucleotide polymorphisms associated with a significant part of the variability in LDL cholesterol and TG concentrations following dietary interventions differing in their fatty acid profiles.
Using an Erythrocyte Fatty Acid Fingerprint to Predict Risk of All-Cause Mortality: the Framingham Offspring Cohort
American Journal of Clinical Nutrition, 2021
In this community-based population of 2,240 subjects in their mid-60s, RBC Fatty Acid patterns were as predictive of risk for death during the next 11 years as standard risk factors (age, sex, total cholesterol, HDL cholesterol, hypertension treatment, systolic blood pressure, smoking status, and prevalent diabetes).
PUFA ω-3 and ω-6 Biomarkers and Sleep: A Pooled Analysis of Cohort Studies on Behalf of the Fatty Acids and Outcomes Research Consortium (FORCE)
American Journal of Clinical Nutrition, 2022
In a pooling analysis of 12 studies from 5 countries, higher blood/tissue concentrations of very long chain omega-3 fatty acids (EPA + DPA + DHA and DHA alone) were associated with lower odds of long sleep duration. These findings highlight the importance of continued study of n-3 PUFAs given the public health implications of poor sleep.
Events
No results.