Among several non-essential health-promoting dietary components, only fiber has a quantified  recommendation for daily intake in the United States. Lutein/zeaxanthin, found in egg yolks and a variety of fruits and vegetables, is associated with healthy ocular tissue, but an amount recommended per day has not been established. Dietary recommendations to achieve optimal health should be based on quantified levels and quality evidence.

The purpose of this research funding opportunity is to determine the strength of evidence linking specific quantities of lutein/zeaxanthin with normal healthy macular pigment optical density (MPOD) among populations relevant to general population in North America. Macular pigment optical density was selected as the outcome through knowledge mapping (Raman, 2015) and subsequent systematic evidence review linking MPOD with visual outcomes (publication in review). The current request is for pre-proposals to address the objectives herein.

Pre-proposals are due February 14, 2020

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This work is supported by the ILSI North America Bioactives Committee