The Committee on Food and Chemical Safety promotes a science-based determination of the chemical safety of foods to support the advancement of public health.
How this committee operates:
The Food and Chemical Safety Committee focuses on many different issues related to the safety of the food supply. To deliver output and impact, the committee works in subgroups focused on specific areas of food and chemical safety. Explore the work of the Committees below.
Areas of Work
Food allergies affect a significant number of children and adults in the US and globally. Potential exposure to food allergens is currently communicated using ambiguous, unhelpful statements such as “may contain” or “packaged in a facility that also processes”. The committee supported the first study of its kind to model peanut allergen dose-responses based on US clinical tests and estimate thresholds of peanut protein that trigger an adverse reaction. The use of allergen response thresholds has the potential to significantly improve food labeling with measurable benefits to allergic individuals (read the project description here and the publication here).
The Committee was a co-sponsor of the National Academies of Sciences, Engineering, and Medicine (NASEM) report Finding a Path to Safety in Food Allergy.
- New Approach Methodologies (NAMs): Risk assessments of some food substances have been shifting to adopt high-throughput, non-animal method strategies for demonstrating safety. These methods, along with new in vitro, in silico and powerful computer modeling tools, are called NAMs. IAFNS efforts focus on available safety assessments of food substances to identify classes of food substances that have leveraged NAMs data to support a regulatory approval. This would include a review of safety determinations by the U.S. FDA in its publicly available GRAS database, as well as those from the European Food Safety Authority.
- Evidence-Based Assessment of Potential Carcinogens in Human Diets: Risk assessment of chemicals that are potentially carcinogenic in humans often relies on extrapolation from bioassays. There is a growing belief in the scientific community that evidence-based risk assessment can replace historical approaches. This project will first categorize potential exposure and mode of action scenarios and then be followed by the development of a framework based on sectoral examples.
- Exposure Assessment for Food Contaminants Through Implementation of Probabilistic Modeling: Toxicological exposure assessments generally rely on deterministic approaches utilizing conservative inputs. Probabilistic assessments can refine deterministic assessments and better account for exposure variability and uncertainty. This project will analyze the current state of exposure modeling by regulatory agencies and highlight the value of integrating probabilistic exposure assessments into regulatory frameworks. It will also address factors that hinder adoption of probabilistic exposure models.
- New Methodologies for Tiered Risk Assessment Using The RISK21 Approach: Programs such ToxCast have generated large amounts of in vitro high‒throughput screening (HTS) data while leaving a gap for best approaches for interpretation and use of this data. To fill this gap, case studies were conducted on two indirect food additive chemicals: sodium (2-pyridylthio)-N-oxide and dibutyltin dichloride. This work highlights the potential utility of the RISK21 approach for interpretation of the ToxCast HTS data, as well as the challenges involved in integrating in vitro HTS data into safety assessments. Access the full publication
Deoxynivalenol (DON), a mycotoxin that infects cereal grains, causes adverse gastrointestinal immunotoxic effects. A recent study examined the impact of recent Codex guidelines on maximum allowable DON levels on global wheat trade and potential global health effects. Stricter DON standards drive developing nations to export their best quality grains and keep more heavily contaminated foods for domestic consumption, resulting in higher mycotoxin exposure. As such, the guidelines may lead to unintended negative health outcomes in developing nations.
Access publications below:
- Risk Assessment of DON exposure in wheat
- Risk-Based Approach to Mycotoxin Mitigation
- Global What Trade and Codex Guidelines for DON
- A Framework for Heavy Metal Exposure Reduction in Human Diets -- Heavy metals (also referred to as toxic elements) such as lead, cadmium, mercury and arsenic are widely present in the environment due to natural occurrence (e.g., in agricultural soils) and anthropomorphic activities. Heavy metals can sometimes unavoidably enter the food supply from various routes such as soil, water and air, as well as agricultural practices. Aligned with FDA’s ‘Closer to Zero’ initiative for reducing toxic elements in foods for babies and infants, the committee has launched two complementary research projects that aim to develop a framework for reducing exposure to heavy metals in foods. Framework elements will include metal/commodity prioritization, concentration ranges, exposure assessments, agricultural practices, and current and future mitigation options along the production and supply chains.
- Review of Regulatory Reference Values and Background Levels for Heavy Metals in the Human Diet -- The U.S. Food and Drug Administration has identified dietary exposure to heavy metals as a public health concern, focusing particularly on arsenic, cadmium, lead and mercury. One way to assess exposure risk is to compare established safe exposure limits (reference values) with current population-based dietary background levels. In a recent paper, information on reference values and dietary background exposure were quickly evaluated and updated. These new regulatory and consumption levels inform a novel, interactive, web-based tool that can be used for screening-level assessments of potential risks of heavy metals in foods and ingredients.
- Metal Dietary Exposure Screening Tool (MDEST) -- This tool is "designed to be used by risk assessors/managers to rapidly evaluate potential public health risk when confronted with the detection of select heavy metals in foods and food ingredients." The heavy metals of interest are arsenic, cadmium, chromium, lead, and mercury. The Committee prioritized the development of a heavy metal screening tool to provide additional context of risk to exposure of five heavy metals found in raw food ingredients. It is important to note, this tool is only one part of a comprehensive decision making process. The tool as well as related case studies and a manuscript are available here.
COMMITTEE MEMBERS
Abbott Nutrition
ADM
Cargill, Incorporated
Campbell Soup
Conagra Brands
General Mills, Inc.
The Hershey Company
International Flavors & Fragrances, Inc.
Keurig Dr Pepper
Kraft Heinz Company
Mondelēz International
ACADEMIC ADVISOR
Norbert Kaminski, PhD, Michigan State University
GOVERNMENT LIAISONS
Suzanne Fitzpatrick, PhD, DABT
U.S. Food and Drug Administration
Center for Food Safety and Applied Nutrition
Randolph Duverna, PhD
U.S. Department of Agriculture
Food Safety & Inspection Service Office of Public Health Service
Katie Weyrauch
U.S Department of Agriculture
Food Safety and Inspection Service
Louis D'Amico, PhD
U.S. Environmental Protection Agency Office of Research and Development
Projects Supported by the Committee:
Publications
Publication Date
White Papers/Reports
No results.
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Events
2019
IAFP 2019 Annual Meeting
July 21, 2019 – July 24, 2019
Louisville, Kentucky, USA
IAFNS is supporting three sessions, a roundtable event and three posters at the 2019 International Association for Food Protection Annual Meeting.
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'_ilsi_date' AND mt2.meta_value BETWEEN '2019-01-01' AND '2019-12-31' ) AND ( mt3.meta_key = '_ilsi_date' AND mt3.meta_value < '2019-12-31' ) ) ) AND ((wp_posts.post_type = 'event' AND (wp_posts.post_status = 'publish' OR wp_posts.post_status = 'acf-disabled'))) GROUP BY wp_posts.ID ORDER BY wp_postmeta.meta_value DESC LIMIT 0, 5 [posts] => Array ( [0] => WP_Post Object ( [ID] => 22183 [post_author] => 67 [post_date] => 2019-03-15 17:54:10 [post_date_gmt] => 2019-03-15 17:54:10 [post_content] =>Each year, the International Association for Food Protection hosts an Annual Meeting, providing attendees with information on current and emerging food safety issues, the latest science, innovative solutions to new and recurring problems, and the opportunity to network with thousands of food safety professionals from around the globe.
IAFNS is supporting three sessions, a roundtable event and three posters at the 2019 IAFP Annual Meeting.
Scientific Sessions:
Managing Large Multidisciplinary/Multi-Institutional Food Safety Projects - Effectively, Impactfully, and with Integrity ExpandMonday, July 22, 2019 | 1:30 - 5:15 PM | Ballroom D
Food safety is a complex and multidisciplinary challenge. Therefore, federally-funded food safety projects, and even industry-centered projects, increasingly involve large, multidisciplinary/multiinstitutional collaborative teams. However, very few individuals thrust into these roles have formal education or training in managing such projects. This symposium brings together a unique and diverse cohort of presenters, ranging from an expert on assessing the effectiveness and impact of research collaborations and centers (with experience on multiple food safety project teams) to experienced managers of such projects (in government, academic, and industry) to a representative of the Scientific Integrity Consortium. The speakers will describe measures for evaluating the effectiveness of such largescale collaborations, identify common features of successful collaborations, share best practices for forming and managing such teams, and outline essential foundational principles for ensuring the quality and integrity of the resulting research. A panel discussion is included to maximize opportunities for attendee interaction with the multiple perspectives provided by the speakers. After this session, attendees will have a better appreciation on how to play together well in the research sandbox.
Conveners: Bradley Marks, Michigan State University; Kendra Nightingale, Texas Tech University; and Isabel Walls, USDA NIFA
Scholarly Assessment of Large Scholarly Collaboration: Measures of Effectiveness and Impact
Denis Gray, PhD, North Carolina State University Managing Government-Academic-Industry Collaborations
Kimberly Cook, PhD, USDA ARS Lessons Learned from Managing NoroCORE, a Large USDA-CAP Project
Lee-Ann Jaykus, PhD, North Carolina State University Managing Food Safety Projects Across Multiple Boundaries - Internally and Externally
Edith Wilkin, PhD, Leprino Foods Report from the Scientific Integrity Consortium: Principles and Best Practices for Scientific Integrity
Linda Harris, PhD, University of California, DavisThis session is supported by the IAFNS Food Microbiology Commitee.
The Mitigation and Regulation of Heat-Formed Substances Produced in Foods During Cooking: What are the Unintended Consequences on Microbial Safety and Public Health? ExpandTuesday, July 23, 2019 | 10:45 AM - 12:15 PM | M107
A growing field in food safety is the focus on the potential risk of heat-formed substances produced during cooking. Compounds that are known as human health hazards are being increasingly identified as heat-formed substances present in food. Two prominent examples of this are acrylamide and furfuryl alcohol, both of which are present in significant amounts in a wide array of foods. This session will help inform how the risk assessment process of heat-formed substances can incorporate the benefits of cooking and cooked food. It will highlight the genetic changes that allowed humans to consume cooked food. The session will then explore the unintended consequences in mitigating heat formed substances, such as introducing microbial hazards. It will address how to assess and communicate these risks to food processors and consumers. The potential impact and implications on the food industry and, ultimately, the end consumer, of using current approaches to assess the potential public health impact of compounds formed during routine cooking of food will be debated.
Convener: Steven Hermansky, PharmD, PhD, DABT, ConAgra Brands
Genetic Evidence of Human Adaptation to a Cooked Diet and its Role in Human Health and Food Safety - Video not available
Steven Hermansky, PharmD, PhD, DABT, ConAgra Brands Balancing Microbial Food Safety Risks with Mitigating Heat-Formed Substances in Foods - Video not available
Scott Hood, PhD, General Mills The Need for a Holistic Toxicological Assessment of Heat-formed Substances within A Food Matrix -Video
Michael Dourson, PhD, DABT, FATS, FSRA, Toxicology Excellence for Risk AssessmentThis session is supported by the IAFNS Food and Chemical Safety Committee.
Let's Hear from Next Generation Food Safety Scientists on Pathogen Behavior in Ready to Eat Foods ExpandWednesday, July 24, 2019 | 1:30 - 3:30 PM | Ballroom E
A current research collaboration between Health Canada, the University of Guelph and North Carolina State University is investigating the survival and inactivation of Listeria monocytogenes, Salmonella, and foodborne viruses during the storage of low moisture foods. This is a wide-ranging research consortium funded by the IAFNS Food Microbiology Committee and includes a number of developing research scientists who will also present their findings. The IAFNS Food Microbiology Committee is committed to proactively improving the understanding and control of microbial food safety hazards to enable scientifically informed decision making. The Committee achieves its mission by funding research that is conducted at institutions who also train the next generation of food safety scientists.
Ready-to-eat low moisture products such as nuts, dried fruits, cereal products, and chocolate are often ingredients used in the manufacturing of many food products. They carry significant potential for the amplification of outbreaks and recalls over a wide variety of products. The research consortium represented by this next generation of food safety experts is studying several aspects of pathogen behavior in low moisture ready-to-eat foods and goes beyond traditional thermal mitigation strategies.
Conveners: Laurie Post, PhD, Deibel Labs; Edith Wilkin, PhD, Leprino Foods
Survival, Inactivation and Detection of Foodborne Viruses During Long Term Storage in Chocolate, Pistachios and Cornflakes
Neda Nasheri, PhD, Health Canada Survival and Virulence of L. monocytogenes During Storage on Low Moisture Foods and Characterization of the Low Moisture Foods Microbiome
Vivian Ly, MSc candidate, University of Guelph Nontraditional Decontamination Methods for Salmonella Reduction in Dried Fruits and Cereals
Kayla Murray, PhD candidate, University of Guelph Identification of Molecular Mechanisms Mediating Long-Term Survival of Salmonella in Pistachios, Dried Apples, and Cornflakes
Victor Oladimeji Jayeola, PhD candidate, North Carolina State UniversityThis session is supported by the IAFNS Food Microbiology Committee.
Roundtable Event:
Is It Time for Food Safety Performance Standards Since Zero Risk Is Not an Option? ExpandMonday, July 22, 2019 | 10:45 AM - 12:15 PM | Ballroom E
Food safety systems rely on verification activities to determine if the system is working as designed and validated. Microbiological performance standards can be used to verify if a processing system is adequately controlling a specific hazard. Performance standards should be set to protect public health. Sampling protocols and microbiological testing methods must be appropriate for the food being tested. In the US poultry industry, performance standards have been in place to measure the prevalence of Salmonella. Over time, the performance standards have changed to reflect the improved conditions in the industry. Prevalence based performance standards may work for other product categories, especially in dry products of raw agricultural products such as wheat flours and the produce area especially for frozen fruits and vegetables. This roundtable discussion will explore the current and potential future uses of performance standards in foods where it is not reasonable to expect zero presence of pathogens.
Convener: Christina Stam, PhD, Kraft Heinz
Panelists:
Craig Hedberg, PhD, University of Minnesota
Candace Doepker, PhD, ToxStrategies
Angie Siemens, PhD, Cargill
Scott Hood, PhD, General Mills
Donna Garren, PhD, American Frozen Food InstituteThis roundtable event is supported by the IAFNS Food Microbiology Committee.
Poster Presentations:
A Novel Simulation Approach to Improving the Effectiveness of Sampling for Bulk Food Products - Video
Eric Cheng, University of Illinois | P1-124 | Monday, July 22, 8:30am - 6:15pm Global Gene Expression Analysis of Salmonella Contaminating Low-Moisture Foods - Video
Victor Oladimeji Jayeola, North Carolina State University | P1-201 | Monday, July 22, 8:30am - 6:15pm Prevalence and Characteristics of Selected Foodborne Bacterial Pathogens in Post-Hurricane Florence Floodwaters - Video
Jeff Niedermeyer, North Carolina State University | P3-161 | Wednesday, July 24, 8:30am - 3:30pmLearn more about the IAFP Annual Meeting here.
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IAFNS is supporting three sessions, a roundtable event and three posters at the 2019 IAFP Annual Meeting.
Scientific Sessions:
Managing Large Multidisciplinary/Multi-Institutional Food Safety Projects - Effectively, Impactfully, and with Integrity ExpandMonday, July 22, 2019 | 1:30 - 5:15 PM | Ballroom D
Food safety is a complex and multidisciplinary challenge. Therefore, federally-funded food safety projects, and even industry-centered projects, increasingly involve large, multidisciplinary/multiinstitutional collaborative teams. However, very few individuals thrust into these roles have formal education or training in managing such projects. This symposium brings together a unique and diverse cohort of presenters, ranging from an expert on assessing the effectiveness and impact of research collaborations and centers (with experience on multiple food safety project teams) to experienced managers of such projects (in government, academic, and industry) to a representative of the Scientific Integrity Consortium. The speakers will describe measures for evaluating the effectiveness of such largescale collaborations, identify common features of successful collaborations, share best practices for forming and managing such teams, and outline essential foundational principles for ensuring the quality and integrity of the resulting research. A panel discussion is included to maximize opportunities for attendee interaction with the multiple perspectives provided by the speakers. After this session, attendees will have a better appreciation on how to play together well in the research sandbox.
Conveners: Bradley Marks, Michigan State University; Kendra Nightingale, Texas Tech University; and Isabel Walls, USDA NIFA
Scholarly Assessment of Large Scholarly Collaboration: Measures of Effectiveness and Impact
Denis Gray, PhD, North Carolina State University Managing Government-Academic-Industry Collaborations
Kimberly Cook, PhD, USDA ARS Lessons Learned from Managing NoroCORE, a Large USDA-CAP Project
Lee-Ann Jaykus, PhD, North Carolina State University Managing Food Safety Projects Across Multiple Boundaries - Internally and Externally
Edith Wilkin, PhD, Leprino Foods Report from the Scientific Integrity Consortium: Principles and Best Practices for Scientific Integrity
Linda Harris, PhD, University of California, DavisThis session is supported by the IAFNS Food Microbiology Commitee.
The Mitigation and Regulation of Heat-Formed Substances Produced in Foods During Cooking: What are the Unintended Consequences on Microbial Safety and Public Health? ExpandTuesday, July 23, 2019 | 10:45 AM - 12:15 PM | M107
A growing field in food safety is the focus on the potential risk of heat-formed substances produced during cooking. Compounds that are known as human health hazards are being increasingly identified as heat-formed substances present in food. Two prominent examples of this are acrylamide and furfuryl alcohol, both of which are present in significant amounts in a wide array of foods. This session will help inform how the risk assessment process of heat-formed substances can incorporate the benefits of cooking and cooked food. It will highlight the genetic changes that allowed humans to consume cooked food. The session will then explore the unintended consequences in mitigating heat formed substances, such as introducing microbial hazards. It will address how to assess and communicate these risks to food processors and consumers. The potential impact and implications on the food industry and, ultimately, the end consumer, of using current approaches to assess the potential public health impact of compounds formed during routine cooking of food will be debated.
Convener: Steven Hermansky, PharmD, PhD, DABT, ConAgra Brands
Genetic Evidence of Human Adaptation to a Cooked Diet and its Role in Human Health and Food Safety - Video not available
Steven Hermansky, PharmD, PhD, DABT, ConAgra Brands Balancing Microbial Food Safety Risks with Mitigating Heat-Formed Substances in Foods - Video not available
Scott Hood, PhD, General Mills The Need for a Holistic Toxicological Assessment of Heat-formed Substances within A Food Matrix -Video
Michael Dourson, PhD, DABT, FATS, FSRA, Toxicology Excellence for Risk AssessmentThis session is supported by the IAFNS Food and Chemical Safety Committee.
Let's Hear from Next Generation Food Safety Scientists on Pathogen Behavior in Ready to Eat Foods ExpandWednesday, July 24, 2019 | 1:30 - 3:30 PM | Ballroom E
A current research collaboration between Health Canada, the University of Guelph and North Carolina State University is investigating the survival and inactivation of Listeria monocytogenes, Salmonella, and foodborne viruses during the storage of low moisture foods. This is a wide-ranging research consortium funded by the IAFNS Food Microbiology Committee and includes a number of developing research scientists who will also present their findings. The IAFNS Food Microbiology Committee is committed to proactively improving the understanding and control of microbial food safety hazards to enable scientifically informed decision making. The Committee achieves its mission by funding research that is conducted at institutions who also train the next generation of food safety scientists.
Ready-to-eat low moisture products such as nuts, dried fruits, cereal products, and chocolate are often ingredients used in the manufacturing of many food products. They carry significant potential for the amplification of outbreaks and recalls over a wide variety of products. The research consortium represented by this next generation of food safety experts is studying several aspects of pathogen behavior in low moisture ready-to-eat foods and goes beyond traditional thermal mitigation strategies.
Conveners: Laurie Post, PhD, Deibel Labs; Edith Wilkin, PhD, Leprino Foods
Survival, Inactivation and Detection of Foodborne Viruses During Long Term Storage in Chocolate, Pistachios and Cornflakes
Neda Nasheri, PhD, Health Canada Survival and Virulence of L. monocytogenes During Storage on Low Moisture Foods and Characterization of the Low Moisture Foods Microbiome
Vivian Ly, MSc candidate, University of Guelph Nontraditional Decontamination Methods for Salmonella Reduction in Dried Fruits and Cereals
Kayla Murray, PhD candidate, University of Guelph Identification of Molecular Mechanisms Mediating Long-Term Survival of Salmonella in Pistachios, Dried Apples, and Cornflakes
Victor Oladimeji Jayeola, PhD candidate, North Carolina State UniversityThis session is supported by the IAFNS Food Microbiology Committee.
Roundtable Event:
Is It Time for Food Safety Performance Standards Since Zero Risk Is Not an Option? ExpandMonday, July 22, 2019 | 10:45 AM - 12:15 PM | Ballroom E
Food safety systems rely on verification activities to determine if the system is working as designed and validated. Microbiological performance standards can be used to verify if a processing system is adequately controlling a specific hazard. Performance standards should be set to protect public health. Sampling protocols and microbiological testing methods must be appropriate for the food being tested. In the US poultry industry, performance standards have been in place to measure the prevalence of Salmonella. Over time, the performance standards have changed to reflect the improved conditions in the industry. Prevalence based performance standards may work for other product categories, especially in dry products of raw agricultural products such as wheat flours and the produce area especially for frozen fruits and vegetables. This roundtable discussion will explore the current and potential future uses of performance standards in foods where it is not reasonable to expect zero presence of pathogens.
Convener: Christina Stam, PhD, Kraft Heinz
Panelists:
Craig Hedberg, PhD, University of Minnesota
Candace Doepker, PhD, ToxStrategies
Angie Siemens, PhD, Cargill
Scott Hood, PhD, General Mills
Donna Garren, PhD, American Frozen Food InstituteThis roundtable event is supported by the IAFNS Food Microbiology Committee.
Poster Presentations:
A Novel Simulation Approach to Improving the Effectiveness of Sampling for Bulk Food Products - Video
Eric Cheng, University of Illinois | P1-124 | Monday, July 22, 8:30am - 6:15pm Global Gene Expression Analysis of Salmonella Contaminating Low-Moisture Foods - Video
Victor Oladimeji Jayeola, North Carolina State University | P1-201 | Monday, July 22, 8:30am - 6:15pm Prevalence and Characteristics of Selected Foodborne Bacterial Pathogens in Post-Hurricane Florence Floodwaters - Video
Jeff Niedermeyer, North Carolina State University | P3-161 | Wednesday, July 24, 8:30am - 3:30pmLearn more about the IAFP Annual Meeting here.
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