Genetic differences have been shown to explain why blood LDL-cholesterol increases in many people fed dairy fat, but in others this results in a neutral or decreased response LDL response. Likewise, specific genetic modifiers have been shown to predict why cholesterol-lowering plant sterols are highly effective in many people, but not in others. Customizing dietary guidance to those likely to realize benefit is paramount to improving efficacy of dietary recommendations. The aim of this study is to develop a model that predicts the effects of lipid-modulating dietary components using genetic multi-SNP algorithms.

Institution: University of Manitoba
Principal Investigator: Peter Jones, PhD
Amount Awarded: $129,800
Year Awarded: 2017

Learn more about the ILSI North America Dietary Lipids Committee.