How this committee operates:
The Food and Chemical Safety committee focuses on many different issues related to the safety of the food supply. In order to maximize output, the committee is segmented into 9 subcommittees, each focusing on a specific area of food and chemical safety. Explore those subcommittees and the impact of their work below.
SOT Annual Meeting & Expo
13-16 March 2017
Areas of Work
The committee hosted a workshop in May 2015; Risk Based Process for Mitigation of Process-Formed Compounds. The objective of this workshop was to discuss a draft decision tree developed by the Technical Committee on Food and Chemical Safety to assess the true impact on risk caused by process-formed compounds. The outcome of the workshop was the ILSI North America decision tree that can be used by the scientific community and has the potential of being adopted as a global regulatory tool for evaluating the impact on risk caused by process-formed compounds.
Read the workshop proceedings
Summer Fellowship Program
This video draws on discussion and conclusions from the ILSI North America workshop “Insights and Perspectives on Emerging Inputs to Weight of Evidence Determinations for Food Safety: Workshop”
The primary limiting factor in longitudinal studies is incomplete data on inorganic arsenic levels in foods combined with the aggregation of consumption of foods with varying arsenic levels into a single category, resulting in exposure misclassification.
The data strongly supports a non-linear dose response for the effects of inorganic arsenic. In various in vitro and in vivo models and in human epidemiology studies there appears to be a threshold for biological responses, including cancer.
The outcome of the workshop was a decision tree that can be used by the scientific community and could form the basis of a global approach to assessing the risks associated with mitigation of process-formed compounds.
The landscape of the food-relevant chemical universe was evaluated using cheminformatics, and subsequently the bioactivity of food-relevant chemicals across the publicly available ToxCast highthroughput screening program was assessed.
Detection of heavy metals at trace or higher levels in foods and food ingredients is not unexpected given the widespread unavoidable presence of several metals in nature, coupled with advancement in analytical methods and lowering limits of detection. To assist risk managers with a rapid risk assessment when facing these situations, a metal dietary exposure screening tool (MDEST) was developed.
Dr. Agnes Karmaus (ILSI North America 2012 Summer Fellow) has been invited to present at EPA’s Computational Toxicology Communities of Practice webinar series on the food-relevant chemicals in ToxCast. This work was supported by the ILSI North America Technical Committee on Food and Chemical Safety.
Sessions organized by ILSI North America’s Food Microbiology and Food & Chemical Safety Committees.
This webinar will provide a forum for integration of scientific disciplines such as food safety, emerging technologies with toxicology; and it will serve as an educational resource to communicate the impact and relevance of food safety and toxicology research with scientists in government, academia and industry.
The Food and Chemical Safety Committee is sponsoring a session on “Risk-Based Assessment of Mycotoxins Mitigation.”